Elucidate the Role of Pulmonary Surfactant in Respiratory Diseases
Deficiencies and defects in the pulmonary surfactant are the cause of some respiratory
diseases such as neonatal respiratory distress syndrome (RDS), acute respiratory
distress syndrome (ARDS), and pulmonary alveolar proteinosis (PAP). Pulmonary
surfactant is also linked to other diseases such as idiopathic pulmonary fibrosis (IPF),
chronic obstructive pulmonary disease (COPD), pneumonia, chronic bronchitis, asthma,
tuberculosis, and sarcoidosis. Using computer simulations, we aim to identify the role of
the pulmonary surfactant in various respiratory diseases, which could illuminate new
potential treatment methods.